The Vortex region is (crudely) estimated by taking the profiles with the mininum temperature at 30 mb corresponding to an area equivalent to that polewards of 80deg S (about 16% of the total area averaged in the lower plot).
The "ozone hole" typically develops throughout August and September, dispersing some time during October as the polar vortex breaks down (2002 - shown in pink - was an unusual year in that the normally-stable polar vortex split in two allowing the ozone-rich air from lower latitudes to enter the polar region).